Viagra became a perfect killer of metastatic cancer

Joe Weider

A new study published in the journal OncoImmunology revealed that Viagra in a combination with flu vaccine can be efficient in fighting metastatic cancer.   These two rather inexpensive and clinically approved drugs may become a solution of major obstacle in fighting cancer. If clinical trials confirm this discovery, Viagra + vaccine can solve the immunity problem, which occurs after operation.   Initially scientist developed Viagra to improve blood flow to cardiac muscle. However, it came into medical practice as a treatment for erectile dysfunction. Recent experiment showed that it… Read More »

Tamoxifen and raloxifene slow down the muscular dystrophy

Joe Weider

Steroids were probably the only cure for recurrent inflammation and disease progression in patients with muscular dystrophy. However, according to the recent study published in American Journal of Pathology a new way of treatment was discovered. Scientists found out that selective estrogen receptor modulators (SERMs), namely Tamoxifen and Raloxifene, can greatly improve the function of respiratory, skeletal and heart muscles. These drugs also enhanced bone thickness in mice of both sexes having the same genetic deviations as in patients with muscular dystrophy. According to Dr. Qi Long Lu, director of the… Read More »

Anapolon  (Oxymetholone)

Joe Weider

In the very beginning Oxymetholone (aka Anadrol, Anapolon) was developed as a cure for bone brittleness, anemia, and for gaining weight in patients with weight loss. Nowadays it belongs to most efficient steroids in sports. Steroid characteristics Anabolic properties – 320% (comparing to testosterone) Androgenic properties – 30% Aromatization (transformation into estrogens) – no Hepatotoxicity – medium Available forms – tablets; rarely oily injections Duration of action – 16 hours Half-life – 9 hours Detection time – up to 3 months Effects Increases muscle mass. Anadrol belongs to a group… Read More »

Testosterone cypionate

Joe Weider

Testosterone cypionate is a long-chained testosterone ester which comes in the form of oily solution. Its half-life is about 2 weeks. Due to the long half life its ability to cause water retention is more expressed than in other steroids.  Usually bodybuilders take it in muscle gaining combinations. It performes the same functions as endogenous testosterone, which is responsible for major male traits  – libido, aggression and muscle growth. It affects anabolic receptors which leads to nitrogen retention in muscle cells and subsequently causing synthesis an accumulation of proteins. Besides… Read More »

Nandrolone

Joe Weider

Nandrolone – (aka Nandrolone Decanoate, 19-nortestosterone, Deca etc.) is an anabolic steroid, which is naturally produced in human organism after heavy exercises or during pregnancy. It has high anabolic and low androgenic properties. Its molecular structure lacks carbon in position 19, therefore it is similar to progestins. That is why its androgenic properties are low, as compared to testosterone.  However, progestin-like structure and its ability to bind to progesterone receptors entails certain side-effects. Steroid characteristics Anabolic properties – 150% (comparing with testosterone) Androgenic properties – 30% Transformation into estrogens –… Read More »

Clenbuterol – a drug for weight loss

Joe Weider

In the beginning Clenbuterol (aka Clen) – was used as a cure for asthma. Nowadays it is a drug of choice among bodybuilders and other athletes owing to its fat-burning properties. In cutting cycles it is usually stacked with Zaditor (Ketotifen) to quicken the weight loss. It does not belong to steroids, therefore women can use it without the hazard of androgenic adverse effects. Its half-life is about 35 hours How it works Clenbuterol has affinity to beta-2 adrenergic receptors in fat and muscle tissues. This binding initiate a chain… Read More »

Testosterone enanthate

Joe Weider

Testosterone enanthate is a representative of testosterone esters. Probably this is one of the most favorite anabolic substances among bodybuilders. It has long period of action, which depends on metabolic rate and hormonal background of an athlete. On average, it remains active for 2 weeks (its half-life is about 7 days). Usually athletes do a weekly injection to keep high concentration of the hormone in blood. Steroid characteristics Anabolic properties – 100% Androgenic properties – 100% Transformation into estrogens – Yes (aromatase inhibitors are required) Suppression of hypothalamus-pituitary-testicles – Yes… Read More »

Halotestin (Fluoxymesterone)

Joe Weider

Fluoxymesterone (Halotestin, Halotest) is an oral steroid with high androgenic and anabolic properties. Its major application is in increasing strength, muscular hardness and aggression, without increase of body weight. Therefore it is taken before competition by those who want to keep weight category (power athletes, fighters etc.). Halotestin has high liver toxicity. Steroid characteristics Anabolic properties – 1900% (comparing to testosterone) Androgenic properties – 850% Transformation into estrogens – No Suppression of HPG axis – Yes Liver toxicity – High Available form – tabs Duration – 6-9 hours Doping test… Read More »

IGF-1 – Insulin-like growth factor-1

Joe Weider

Insulin-like growth factor-1 (also known as somatomedin С, IGF-1) is a peptide hormone, which is similar to insulin. It is the main intermediate of growth hormone activity. Therefore it is responsible for childhood growth and besides produces anabolic effect in adults, initiating muscular hyperplasia. Its effects are identical to the effects of human growth hormone (HGH), however the latter doesn’t act independently. Today we know that HGH forces the liver to release IGF-1 into the blood, which in turn produces “growth hormone effects” – fat burning, growth of muscle fibers… Read More »

Sustanon 250

Joe Weider

Sustanon 250 is a mix of various testosterone esters, also known under such trade names as Sustamed, Tetrasterone, Sustager etc. In medical practice it was initially used as a hormonal replacement therapy in patients with insufficient testosterone production. Sustanon formula includes 4 different testosterone esters: 30mg Testosterone propionate 60mg Testosterone phenylpropionate 60mg Testosterone Isocaproate 100mg Testosterone Decanoate Note that the storage of testosterone in bottles with rubber caps is strictly prohibited. Each ester has its own rate of absorption and time of action. This combination allows you to keep high… Read More »