Author: Joe Weider

Clenbuterol – a drug for weight loss

Joe Weider

In the beginning Clenbuterol (aka Clen) – was used as a cure for asthma. Nowadays it is a drug of choice among bodybuilders and other athletes owing to its fat-burning properties. In cutting cycles it is usually stacked with Zaditor (Ketotifen) to quicken the weight loss. It does not belong to steroids, therefore women can use it without the hazard of androgenic adverse effects. Its half-life is about 35 hours How it works Clenbuterol has affinity to beta-2 adrenergic receptors in fat and muscle tissues. This binding initiate a chain… Read More »

Testosterone enanthate

Joe Weider

Testosterone enanthate is a representative of testosterone esters. Probably this is one of the most favorite anabolic substances among bodybuilders. It has long period of action, which depends on metabolic rate and hormonal background of an athlete. On average, it remains active for 2 weeks (its half-life is about 7 days). Usually athletes do a weekly injection to keep high concentration of the hormone in blood. Steroid characteristics Anabolic properties – 100% Androgenic properties – 100% Transformation into estrogens – Yes (aromatase inhibitors are required) Suppression of hypothalamus-pituitary-testicles – Yes… Read More »

Halotestin (Fluoxymesterone)

Joe Weider

Fluoxymesterone (Halotestin, Halotest) is an oral steroid with high androgenic and anabolic properties. Its major application is in increasing strength, muscular hardness and aggression, without increase of body weight. Therefore it is taken before competition by those who want to keep weight category (power athletes, fighters etc.). Halotestin has high liver toxicity. Steroid characteristics Anabolic properties – 1900% (comparing to testosterone) Androgenic properties – 850% Transformation into estrogens – No Suppression of HPG axis – Yes Liver toxicity – High Available form – tabs Duration – 6-9 hours Doping test… Read More »

IGF-1 – Insulin-like growth factor-1

Joe Weider

Insulin-like growth factor-1 (also known as somatomedin С, IGF-1) is a peptide hormone, which is similar to insulin. It is the main intermediate of growth hormone activity. Therefore it is responsible for childhood growth and besides produces anabolic effect in adults, initiating muscular hyperplasia. Its effects are identical to the effects of human growth hormone (HGH), however the latter doesn’t act independently. Today we know that HGH forces the liver to release IGF-1 into the blood, which in turn produces “growth hormone effects” – fat burning, growth of muscle fibers… Read More »

Sustanon 250

Joe Weider

Sustanon 250 is a mix of various testosterone esters, also known under such trade names as Sustamed, Tetrasterone, Sustager etc. In medical practice it was initially used as a hormonal replacement therapy in patients with insufficient testosterone production. Sustanon formula includes 4 different testosterone esters: 30mg Testosterone propionate 60mg Testosterone phenylpropionate 60mg Testosterone Isocaproate 100mg Testosterone Decanoate Note that the storage of testosterone in bottles with rubber caps is strictly prohibited. Each ester has its own rate of absorption and time of action. This combination allows you to keep high… Read More »

SARMs – Selective Androgen Receptor Modulators

Joe Weider

SARMs – Selective Androgen Receptor Modulators SARMs belong to a group of molecules that selectively bind to sex hormone receptors. By their action they are similar to SERMs -Selective Estrogen Receptor Modulators (e.g. Clomiphene and Tamoxifen (Nolvadex)) with the only difference that they bind to androgen receptors. As SARMs are not steroids, they do not undergo conversion by steroid enzymes, therefore there are no undesirable side-effects. The initial aim of SARMs was to reduce the adverse effects of testosterone on prostate. But later scientists found out that they can increase… Read More »

Masteron (Drostanolone Propionate)

Joe Weider

Masteron (also Drostanolone, Drolban, Metormon, Permastril, Mastager, etc.) is an anabolic steroid which originates from dihydrotestosterone. It has high androgenic and moderate anabolic properties. Masteron is not an aromatizable steroid (i.e. there is no conversion into estrogen), moreover it acts as aromatase inhibitor. Therefore there is no risk of estrogen related side-effects, such as gynecomastia and water retention. In clinical practice it was used as a cure for breast cancer in women, however, due to the high risks of virilization, it is practically out of use today. Due to its… Read More »

Primobolan

Joe Weider

Primobolan (Methenolone) is an anabolic steroid, which originates from dihydrotestosterone. It has weak androgenic and moderate anabolic properties. This hormone is available in the form of tablets (Oral Primobolan), and injectable form (Primobolan Depot). Injectable version of this substance (Primobolan Depot) is an Enanthate ester of Methenolone, which has prolonged action (about two weeks). It is regarded as one of the safest steroid. In medical practice it was successfully applied in treatment of underweight children, osteoporosis and sarcopenia. The major inconvenience is that its injection is rather painful. A tablet… Read More »

Anavar (oxandrolone)

Joe Weider

Anavar (oxandrolone) Oxandrolone (also Oxanoger,  Anavar, Oxandrin etc.) is one of the safest oral steroids. It has high anabolic index, meanwhile its androgenic properties are extremely low. This steroid greatly stimulates immunity and increases insulin sensitivity. Therefore it was initially introduced into the medical practice as medication for immunocompromised HIV patients and overweight associated diabetes. It is also effective as a treatment of osteoporosis, osteochondrosis, Turner’s syndrome, anemia etc. Later, when its anabolic properties were discovered, it became popular among bodybuilders. Steroid characteristics Anabolic properties – 400% of testosterone Androgenic… Read More »

Steroid Combinations for Gaining Muscle Mass

Joe Weider

Steroid Combinations for Gaining Muscle Mass It’s not a secret that all professional bodybuilders take combinations of steroids to achieve optimal results. But sometimes it’s hard to find safe and efficient steroid combinations. So, in this article we collected classical stacking of steroids for gaining muscle mass, also concerning the issues of safety. Usually steroid combinations involve stacking of androgenic substances with predominantly anabolic ones. One should mention that :boldenone, Methenolone, Nandrolone, Oxandrolone and Stanozolol belong to anabolic group of steroids, while Testosterone Undecanoate and Oxymetholone belong to androgenic substances.… Read More »